Digital technology innovation is the core driving force of the digital economy development. An in-depth study on the regional distribution pattern and its formation mechanism of digital technology innovation is helpful to promote the regional digital economy and its high-quality development. Based on the corresponding relationship between digital economy and international patent classification,this paper obtains the patent output data of digital economy from 2003 to 2018,and analyzes the spatial and temporal pattern of digital technology innovation and its factors in the Yangtze River Delta. The results show that: 1) The scale and vitality of digital technology innovation show obvious spatial differentiation,and form a pattern of agglomeration distribution in Shanghai,southern Jiangsu,northeastern Zhejiang and central Anhui,and the agglomeration degree is decreasing. 2) The results of Moran' I and spatial measurement show that the scale and vitality of digital technology innovation in the Yangtze River Delta region have a significant spatial spillover effect. 3) The results confirm that economic development,human capital,capital enrichment,digital access and infrastructure construction have a significant positive impact on digital technology innovation,while environmental pollution has a significant negative impact. The transformation of the technological and economic paradigm of technological innovation provides a new opportunity for the economic development of the relatively backward areas to catch up. In the future,the high-quality development of central and western regions should pay more attention to the cultivation of the core competitiveness of digital economy,and strengthen the construction of digital infrastructure and the construction of digital technology innovation ability.
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